COVID-19 vaccines do not change or interact with your DNA in any way.
Both messenger RNA (mRNA) and viral vector COVID-19 vaccines work by delivering instructions (genetic material) to our cells to start building protection against the virus that causes COVID-19.
After the body produces an immune response, it discards all the vaccine ingredients just as it would discard any information that cells no longer need. This process is a part of normal body functioning.
The genetic material delivered by mRNA vaccines never enters the nucleus of your cells, which is where your DNA is kept. Viral vector COVID-19 vaccines deliver genetic material to the cell nucleus to allow our cells to build protection against COVID-19. However, the vector virus does not have the machinery needed to integrate its genetic material into our DNA, so it cannot alter our DNA.
Learn more about how COVID-19 vaccines work.